Opaleye Management Inc.: insider trades

Every open market trade Opaleye Management Inc. has filed with the SEC, when each filing appeared, and how the buys did against the S&P 500 once the filing was public.

Key Facts

  • Opaleye Management Inc. is listed as 10% Owner at ACOG, ETON, GRCE, SLGL, SNWV.
  • Between 2026-03-10 (10 March 2026) and 2026-09-28 (28 September 2026) Opaleye Management Inc. filed 43 open market buys worth $11M and 8 open market sales worth $7.4M.
  • Across 10 scored buys, Opaleye Management Inc. averaged +15.1% against the S&P 500 (SPY) over the 90 days after disclosure, with 80% of them ahead of the index. That result is based on too few months of entries (3) to judge.
  • Data as of 2026-09-29 (29 September 2026).
Open market buys 43 $11M
Open market sales 8 $7.4M
Avg vs S&P, 90d +15.1% 10 scored buys
Beat the S&P 80% 90 days after entry

Would copying Opaleye Management Inc. have paid?

prices as of 2026-09-28

The result. Across 10 scored buys, Opaleye Management Inc. averaged +15.1% against the S&P 500 (SPY) over the 90 days after disclosure, with 80% of them ahead of the index. That result is based on too few months of entries (3) to judge.

Average return of Opaleye Management Inc.'s open market buys against the S&P 500.
Days after entryScored buysAvg vs S&PBeat S&PEntry monthst statisticReading
30 days 16 +10.5% 69% 5 n/a based on too few months of entries (5) to judge
90 days 10 +15.1% 80% 3 n/a based on too few months of entries (3) to judge
180 days 6 +25.4% 83% 2 n/a too few trades to draw a conclusion
Opaleye Management Inc.: average excess return after disclosure Opaleye Management Inc.'s scored buys averaged +25.37% against the S&P 500 by day 180 after entry, across 6 buys. The grey line is the average for all insiders. -9.9% +2.6% +15.1% +27.5% +40.0% 0d28d56d84d112d140d168d
Opaleye Management Inc.'s scored buys averaged +25.37% against the S&P 500 by day 180 after entry, across 6 buys. The grey line is the average for all insiders.
Opaleye Management Inc.: average excess return after disclosure
Days after entryOpaleye Management Inc.All insiders
0d0.00%0.00%
7d+1.52%-0.65%
14d+2.07%-1.00%
21d+7.72%-1.53%
28d+10.57%-1.90%
35d+9.24%-1.95%
42d+7.39%-2.68%
49d+4.85%-3.73%
56d+3.24%-4.21%
63d+3.70%-3.93%
70d+5.57%-3.84%
77d+6.13%-4.42%
84d+12.12%-3.24%
91d+16.50%-3.26%
98d+19.99%-3.90%
105d+21.65%-4.80%
112d+24.55%-5.04%
119d+27.65%-6.45%
126d+25.82%-7.64%
133d+28.66%-8.05%
140d+27.06%-8.59%
147d+31.16%-9.81%
154d+36.01%-9.90%
161d+33.75%-9.69%
168d+30.48%-9.86%
175d+27.10%-9.62%
180d+25.37%-9.58%

Stocks traded

  1. ACOG26 trades, $4.0M
  2. SLGL12 trades, $6.7M
  3. GRCE5 trades, $87.8K
  4. ETON4 trades, $5.8M
  5. SNWV4 trades, $1.6M

Every open market trade

as of 2026-09-29
51 trades.
Open market trades filed by Opaleye Management Inc., newest first.
FiledStockTypeSharesPriceValue90 day vs S&P
28 Sep 2026 ACOG buy 13,426 $8.47 $114K n/a
28 Sep 2026 ACOG buy 18,337 $8.57 $157K n/a
23 Sep 2026 GRCE buy 9,771 $2.10 $20.5K n/a
23 Sep 2026 GRCE buy 5,318 $2.10 $11.2K n/a
14 Sep 2026 SLGL buy 1,493 $65.94 $98.5K n/a
14 Sep 2026 SLGL buy 1,631 $66.80 $109K n/a
10 Sep 2026 GRCE buy 9,393 $2.10 $19.7K n/a
10 Sep 2026 GRCE buy 5,836 $2.09 $12.2K n/a
9 Sep 2026 SLGL buy 3,861 $68.82 $266K n/a
9 Sep 2026 SLGL buy 3,097 $68.70 $213K n/a
9 Sep 2026 SLGL buy 3,018 $69.14 $209K n/a
31 Aug 2026 SLGL buy 35,113 $69.32 $2.4M n/a
31 Aug 2026 SLGL buy 5,217 $68.27 $356K n/a
19 Aug 2026 GRCE buy 11,608 $2.09 $24.2K n/a
4 Aug 2026 ACOG buy 50,000 $8.00 $400K n/a
4 Aug 2026 ACOG buy 2,900 $7.92 $23.0K n/a
28 Jul 2026 ACOG buy 130 $7.90 $1.0K n/a
24 Jul 2026 ACOG buy 49,849 $7.80 $389K n/a
24 Jul 2026 ACOG buy 150,237 $7.83 $1.2M n/a
16 Jul 2026 ETON sell 28,315 $37.54 $1.1M n/a
10 Jul 2026 SLGL buy 300 $73.69 $22.1K n/a
10 Jul 2026 SLGL buy 229 $73.95 $16.9K n/a
7 Jul 2026 ETON sell 10,000 $38.00 $380K n/a
7 Jul 2026 ETON sell 26,685 $38.37 $1.0M n/a
7 Jul 2026 ETON sell 90,000 $37.39 $3.4M n/a
2 Jul 2026 SLGL buy 1,400 $71.97 $101K n/a
2 Jul 2026 SLGL buy 312 $71.99 $22.5K n/a
29 Jun 2026 ACOG buy 197 $6.50 $1.3K +16.3%
29 Jun 2026 ACOG buy 152,336 $6.40 $975K +16.3%
15 Jun 2026 ACOG buy 273 $5.93 $1.6K +43.3%
15 Jun 2026 ACOG buy 4,550 $5.99 $27.3K +43.3%
15 Jun 2026 ACOG buy 2,862 $5.91 $16.9K +43.3%
9 Jun 2026 ACOG buy 10,054 $5.83 $58.6K +53.1%
29 May 2026 ACOG buy 1,161 $5.73 $6.7K +42.8%
29 May 2026 ACOG buy 70,577 $5.90 $416K +42.8%
29 May 2026 ACOG buy 2,000 $5.83 $11.7K +42.8%
30 Apr 2026 SNWV sell 46,288 $18.47 $855K n/a
30 Apr 2026 SNWV sell 24,360 $17.25 $420K n/a
21 Apr 2026 SNWV sell 16,267 $20.46 $333K n/a
21 Apr 2026 SNWV sell 202 $20.50 $4.1K n/a
31 Mar 2026 ACOG buy 1,850 $4.99 $9.2K +6.9%
31 Mar 2026 ACOG buy 10,000 $5.08 $50.8K +6.9%
26 Mar 2026 ACOG buy 4,182 $5.59 $23.4K +11.9%
26 Mar 2026 ACOG buy 8,581 $5.43 $46.6K +11.9%
26 Mar 2026 ACOG buy 7,319 $5.28 $38.7K +11.9%
24 Mar 2026 SLGL buy 39,665 $72.00 $2.9M -21.9%
20 Mar 2026 ACOG buy 2,481 $5.75 $14.3K +4.9%
20 Mar 2026 ACOG buy 2,094 $5.71 $11.9K +4.9%
18 Mar 2026 ACOG buy 1,331 $5.78 $7.7K +1.8%
10 Mar 2026 ACOG buy 1,900 $5.80 $11.0K -7.6%
10 Mar 2026 ACOG buy 2,179 $5.85 $12.7K -7.6%

Insider sales are shown but not scored, because they are often planned for tax or diversification reasons.

Frequently asked questions

What has Opaleye Management Inc. bought and sold?

Between 2026-03-10 (10 March 2026) and 2026-09-28 (28 September 2026) Opaleye Management Inc. filed 43 open market buys worth $11M and 8 open market sales worth $7.4M.

Did Opaleye Management Inc.'s buys beat the market?

Across 10 scored buys, Opaleye Management Inc. averaged +15.1% against the S&P 500 (SPY) over the 90 days after disclosure, with 80% of them ahead of the index. That result is based on too few months of entries (3) to judge. Insider sales are not scored because they are often planned for tax or diversification reasons.

Sources: Insider trades: SEC Form 4 filings, collected from Finviz. Prices: Yahoo Finance daily adjusted closes. Data as of 2026-09-29 (29 September 2026). About these sources.

Not investment advice. Past disclosed trades do not predict future returns. Disclosures are published late, so the trades shown are ones you could only have copied after the fact. Talk to a licensed adviser before you invest.